Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP-Intolerant OSA Patients.

In the secondary model specification excluding constituent variables of mSASI and FRS, pre‐treatment mSASI remained positively associated with FRS, although the effect size was smaller and did not reach statistical significance ( β = 0.55, 95% CI –4.6 to 5.7, p = 0.8; Table S1 ). 4 Discussion Cardiovascular risk is an important consideration in the management of OSA, which has been linked to HTN, Afib, other arrhythmias, CHF, CAD, CVA/TIA, T2DM, and metabolic syndrome [ 22 ].

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