Specific gut microbiota alterations and metabolic deficits in Parkinson's disease: a controlled comparison with functional constipation.

At the KEGG Level 3 pathway level, the PDC group showed an overall trend toward reduced predicted functional abundance across several nominally significant pathways, suggesting broader metabolic impairment beyond taxonomic shifts alone.

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KEGG Level 3 pathway analysis revealed multiple nominally significant functional differences between the two groups, which are summarized in Figure 4 .

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