In the apex and middle regions, 7,8-DHF produced a partial improvement in Ribbon/IHC relative to the Blast + Vehicle group (apex, 13.23 ± 0.25; middle, 12.76 ± 0.48 ribbons/inner hair cell), although this did not reach statistical significance ( Figure 4B ).
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TrkB activation mitigates blast-induced cochlear pathology and promotes auditory recovery in a compressed-air blast model.
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