Xinnaoxin tablets ameliorate high-altitude polycythemia-associated cardiac injury by regulating the NF-κB, MAPK, and PI3K/AKT signaling pathways.

Although cardiac SOD activity showed a decreasing trend under HH and an increasing trend with low-dose XNX, these changes were not statistically significant ( Figure 6G ).

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Although RVID showed an increasing trend under HH conditions and a decrease following drug administration, these changes did not reach statistical significance.

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