Barely Significant
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Lipidomic characterization of bile and serum reveals an altered lipid landscape in end-stage primary sclerosing cholangitis.

Sci Rep · 2026 · PMC13253874 · PMID 42000740

Europe PMCDOI
3
hedged sentences
0.7000
closest p · 14.0× alpha
0.7000
boldest claim

The sentences

did not reach statistical significanceP = 0.7not close (p > 0.1)
Total LPA levels were significantly elevated in bile and peripheral serum from PSC patients and a similar upward trend was also observed in portal vein samples although it did not reach statistical significance (P = 0.7).

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a decreasing trendno p-value reported
In peripheral and portal serum, although these changes ether PE species showed a decreasing trend in PSC, the changes were not statistically significant (Supplementary Fig. 1 B).

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an increasing trendno p-value reported
Similarly, PE species demonstrated an increasing trend in PSC, while ether-linked PEs showed a decreased trend (Fig. 3 C).

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