Machine learning-based model for prediction of carbamazepine- and allopurinol-induced severe cutaneous adverse reactions in Vietnamese.

World Allergy Organ J · 2026 · PMC13254861 · PMID 42292762

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did not reach statistical significanceno p-value reported

Several other HLA alleles showed weaker associations (OR < 5) that did not reach statistical significance at the conventional α = 0.05 level.

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not as significantno p-value reported

Two variants, chr9:18681697: T > G on the ADAMTSL1 gene on chromosome 9 and chr7:28410809:C > CAGG on the CREB5 gene on chromosome 7, also contribute to SCARs induced by CBZ, although not as significant as HLA-B∗15:02:01.

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