Cognitive and structural brain changes in ofatumumab-treated multiple sclerosis: A longitudinal study.

Neurotherapeutics · 2026 · PMC13255068 · PMID 42235093

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did not reach statistical significanceno p-value reported

In patients with baseline SDMT z-score ≤ −1, 12-month changes in deep GM volume were significantly associated with 12-month SDMT change ( β = −55.91, 95% CI −98.25 to −13.58; p = 0.012), whereas the association with thalamic volume was borderline and did not reach statistical significance ( Fig. 3 ).

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