Barely Significant
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Prognostic value of cachexia index in HR +/HER2 - metastatic breast cancer treated with CDK4/6 inhibitors.

BMC Cancer · 2026 · PMC13255495 · PMID 42045838

1
hedged sentence
0.0590
closest p · 1.2× alpha
0.0590
boldest claim

The sentences

showed a trendp = 0.059so close (0.05 < p ≤ 0.1)
Low SMD showed a trend toward reduced OS (HR 0.49, 95% CI 0.23–1.03, p = 0.059), whereas low L3 SMI was significantly associated with shorter OS (HR 0.37, 95% CI 0.16–0.87, p = 0.023).

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