Molecular Characterization of Small Extracellular Vesicles in Pancreatic Cancer Patients Treated with Neoadjuvant Chemotherapy Followed by Stereotactic Body Radiation.

We observed a decreased trend for CA19-9 expression following FOLFIRINOX and SBRT, although this did not reach statistical significance ( Figure 3 C); however, GEM-ABRAX treatment and SBRT significantly reduced the levels of CA19-9 on sEVs’ surface ( Figure 3 D). 3.3. miRNA Expression in sEVs Next, we analyzed the expression levels of 11 miRNAs (miR-155-5p, miR-106b-5p, miR-16-5p, miR-21-5p, miR-194-5p, miR-181-5p, miR-17-5p, miR-196a-5p, miR-320a-5p, miR-210-3p, miR-50-5p) associated with pancreatic cancer.

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