showed a trendp = 0.074
Bone metastasis showed a trend toward shorter PFS (HR = 2.43; 95% CI, 0.92–6.41; p = 0.074) but did not reach significance for OS (HR = 2.04; 95% CI, 0.63–6.55; p = 0.233) ( Supplementary Table S3, Supplementary Figure S1A,B ). 3.4.