Divergent Roles of VEGF and TNF-α in Functional Impairment Among Patients with Carpal Tunnel Syndrome.

Int J Mol Sci · 2026 · PMC13257110 · PMID 42278499

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.1750

boldest claim

The sentences

a statistical trendp = 0.062so close (0.05 < p ≤ 0.1)

Fractalkine The result for fractalkine ( CX3CL1 ) showed only a statistical trend ( p = 0.062) that did not meet the significance threshold; accordingly, this finding should not be over-interpreted.

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did not reach statistical significancep = 0.175not close (p > 0.1)

Critically, the overall model did not reach statistical significance (χ 2 (12) = 16.4, p = 0.175, R 2 = 0.196), indicating that the cytokine panel explains only 19.6% of variability in functional disability; the majority of variability remains unexplained.

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