Hemp Seed Protein-Derived Lipase Inhibitory Peptides Attenuate High-Fat Diet-Induced Obesity: Evidence from Intestinal Fat Digestion and Gut-Liver Axis Regulation.

Foods · 2026 · PMC13257395 · PMID 42279825

Europe PMC DOI

hedged sentences

0.0003

closest p · 0.0× alpha

0.1400

boldest claim

The sentences

highly significantp = 0.00025actually significant

The Chao1 index showed highly significant differences among groups ( p = 0.00025), with the HFD group exhibiting markedly reduced microbial richness compared with the ND group.

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did not reach statistical significancep = 0.14not close (p > 0.1)

The Simpson index showed an improving trend but did not reach statistical significance ( p = 0.14).

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an increasing trendno p-value reported

At the phylum level ( Figure 4 C), HFD induced a typical obesity-associated dysbiotic signature characterized by increased Firmicutes_D, decreased Bacteroidota and consequently an elevated F/B ratio, accompanied by an increasing trend of Desulfobacterota_I.

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