Development of a Metagenomics-Guided Personalized Synbiotic Protocol for Children with Autism Spectrum Disorder: An Exploratory Case Series.

Nutrients · 2026 · PMC13257912 · PMID 42280338

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did not reach statistical significanceno p-value reported

conducted a clinical trial utilizing the probiotic VISBIOME to treat children with ASD accompanied by gastrointestinal symptoms; they found that the probiotic treatment significantly alleviated specific symptoms of gastrointestinal discomfort selected by parents, although the primary outcome measures regarding gastrointestinal quality of life did not reach statistical significance [ 29 ].

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