Single-cell transcriptomic profiling reveals CD27<sup>+</sup> cytotoxic T Cell heterogeneity and exhaustion dynamics in colorectal cancer tumor microenvironment.

Front Genet · 2026 · PMC13258542 · PMID 42294500

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did not reach statistical significanceno p-value reported

Exploratory survival analysis (HR = 0.505, p = 0.673) did not reach statistical significance and is presented as hypothesis-generating only, highlighting the need for prospective validation in larger cohorts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Single-cell transcriptomic profiling reveals CD27&lt;sup&gt;+&lt;/sup&gt; cytotoxic T Cell heterogeneity and exhaustion dynamics in colorectal cancer tumor microenvironment.

The sentences

Single-cell transcriptomic profiling reveals CD27<sup>+</sup> cytotoxic T Cell heterogeneity and exhaustion dynamics in colorectal cancer tumor microenvironment.