Endothelial, cytokine, and Th1/cellular host biomarkers discriminate complicated osteoarticular tuberculosis: a prospective single-center cohort study with ROC analysis.

Front Cell Infect Microbiol · 2026 · PMC13259751 · PMID 42291296

Europe PMC DOI

hedged sentence

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

All remaining markers — CD3 + , CD4 + , CD16 + , CD20 + , and CD25 + percentages; IL-1β and IL-4; IgA and IgM; and tPA — fell into the low-discrimination tier (AUC 0.56–0.66) and did not reach statistical significance individually (p > 0.05).

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