Cannabis and tobacco co-use predicts psychosis in clinical high risk cohorts.

Nat Ment Health · 2026 · PMC13259916 · PMID 42291778

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did not reach statistical significanceno p-value reported

Higher frequency of cannabis use remained positively associated with higher risk of conversion to psychosis (HR = 1.16, 95% CI [1.00–1.35], P = 0.055) when controlling for tobacco use, but the association was reduced and did not reach statistical significance.

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