Correlation between tumor mutational burden and CT radiographic features in EGFR exon 19 deletion-mutated lung adenocarcinoma: a diagnostic accuracy study.

Pleural indentation exhibited a borderline significant intergroup disparity (χ 2 = 3.289, p = 0.07).

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The predictive effect of pleural indentation sign did not reach statistical significance (Wald = 3.223, p = 0.073) (see Table 3 for details). 3.5 Multivariate logistic regression analysis of predictors for high TMB Multivariate logistic regression analysis, which included age, smoking history, and the significant imaging features from the univariate analysis, confirmed that maximum tumor diameter (OR, 1.13; 95% CI, 1.05–1.21; p = 0.001), spiculation (OR, 2.34; 95% CI, 1.11–4.95; p = 0.026), lobulation (OR, 2.18; 95% CI, 1.01–4.71; p = 0.047), and vascular convergence (OR, 2.07; 95% CI, 1.02–4.21; p = 0.044) remained independent predictors of high TMB.

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