High-dimensional immune profiling of peripheral blood identifies immune correlates of anti-PD-1/PD-L1 resistance in oncogenic driver mutation-positive NSCLC.

Front Immunol · 2026 · PMC13260270 · PMID 42292481

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hedged sentences

0.0504

closest p · 1.0× alpha

0.0504

boldest claim

The sentences

a trend toward significanceP=0.0504so close (0.05 < p ≤ 0.1)

Among these clusters, only CD27 + PD-1 - effector memory CD4 + T cell (excluding skin-homing T cells) showed a trend toward significance in dynamic differences between WT and MT patients ( P=0.0504 ; Supplementary Figure 9A ).

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showed a trendno p-value reported

While MT patients showed a trend toward decreased CD4 + T cell and increased CD8 + T cells, the change was not statistically significant ( P = 0.0681 ).

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