Body mass index adjusted aspirin dosing does not overcome pharmacokinetic and pharmacodynamic disadvantages in obese pregnant women at risk for preeclampsia: a prospective cohort study.

Front Med (Lausanne) · 2026 · PMC13260331 · PMID 42292185

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

near-significantp = 0.051so close (0.05 < p ≤ 0.1)

Higher follow-up salicylate concentrations showed a near-significant association with greater TxB2 reduction (r = −0.337, p = 0.051), indicating that adequate drug exposure is necessary for effective thromboxane inhibition.

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