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MRI-guided risk stratification for neoadjuvant immunotherapy in rectal cancer.

Front Immunol · 2026 · PMC13260345 · PMID 42292396

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hedged sentence
0.1070
closest p · 2.1× alpha
0.1070
boldest claim

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did not reach statistical significanceP = 0.107not close (p > 0.1)
In the subgroup with tumor length ≥ 5 cm, nICRT also showed a numerically higher pCR rate, although the difference did not reach statistical significance (OR, 2.99; 95% CI, 0.79–11.27; P = 0.107). 3.6 ROC analysis The MRI-based risk stratification system combining mrEMVI, mrMRF, and tumor length ≥ 5 cm yielded an AUC of 0.835 (95% CI, 0.767–0.902), indicating good discrimination between patients with and without pCR ( Figure 4 ).

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