Altered early-life gut microbiota in offspring of pregnancies complicated by CHD-associated pulmonary hypertension.

Front Microbiomes · 2026 · PMC13260587 · PMID 42293160

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did not reach statistical significanceno p-value reported

Although the overall community structures of the PH and NC groups appeared to be slightly different, these differences did not reach statistical significance.

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an increasing trendno p-value reported

The results showed that 2-dehydropantoate 2-reductase (EC:1.1.1.169), which participates in pantothenate/coenzyme A biosynthesis, was slightly higher in the PH group than in the NC group, and that alkanesulfonate monooxygenase (EC:1.14.14.5), which is related to organosulfonate degradation and sulfur metabolism, also exhibited an increasing trend in the PH group.

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