Effect of IL-6 inhibition on lipoprotein(a) levels: A systematic review and meta-analysis.

Am J Prev Cardiol · 2026 · PMC13261205 · PMID 42291085

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did not reach statistical significanceno p-value reported

Participants showed an SMD of -0.26 (95 % CI -0.53 to 0.01; P = .06), indicating small reductions in Lp(a) levels with ziltivekimab treatment that did not reach statistical significance compared with placebo treatment ( Fig. 3 A ).

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