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A polypill strategy for lipid lowering and anti-platelet therapy after acute coronary syndrome: A pilot randomized controlled trial.

Am J Prev Cardiol · 2026 · PMC13261256 · PMID 42291077

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While between-group differences did not reach statistical significance, the observed trends toward enhanced benefits among patients with poor baseline adherence represent important mechanistic signals that may become more pronounced over longer follow-up as adherence patterns degrade, supporting the rationale for adequately powered, longer-duration trials.

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