Intranasal Dexmedetomidine Versus Esketamine As Premedication for the Sedation of Pediatric Patients: A Systematic Review and Meta-Analysis.

Cureus · 2026 · PMC13261321 · PMID 42291934

Europe PMC DOI

hedged sentence

0.1400

closest p · 2.8× alpha

0.1400

boldest claim

The sentences

did not reach statistical significancep=0.14not close (p > 0.1)

In the bronchoscopy subgroup where dexmedetomidine was used at the lower dose of 1 μg/kg, the effect was reversed, with esketamine showing a numerically lower ED incidence, though this did not reach statistical significance (RR 2.60 (0.74, 9.15); p=0.14).

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