Quantitative prediction of siRNA complexation by ionizable drugs enables their codelivery in nanoparticles.

Sci Adv · 2026 · PMC13262629 · PMID 42284421

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closest p

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a clear trendno p-value reported

While we thought that p K a would be an important factor in siRNA complexation, a plot of relative fluorescence by calculated p K a values reported in DrugBank did not show a clear trend (fig.

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