Barely Significant
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Global and Chinese co-occurrence patterns association with socio-demographic index for congenital heart disease and Down syndrome, 1990-2021.

Transl Pediatr · 2026 · PMC13263433 · PMID 42292606

2
hedged sentences
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

did not reach statistical significanceP=0.09so close (0.05 < p ≤ 0.1)
The age-standardized prevalence rate exhibited a slight downward trend, though it did not reach statistical significance (EAPC: −0.18%, P=0.09).

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a decreasing trendno p-value reported
an increasing trendno p-value reported
An EAPC greater than 0 indicates an increasing trend in ASR over time, whereas an EAPC less than 0 signifies a decreasing trend.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.