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Development and external validation of a multivariable nomogram for predicting severe immune checkpoint inhibitor-associated myocarditis in advanced lung cancer.

Transl Lung Cancer Res · 2026 · PMC13263832 · PMID 42291359

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Although ECG did not reach statistical significance in our dataset, its effect direction mirrors published data: multicenter reports indicate that ~90% of severe ICIM cases develop new ECG changes, including ST-T abnormalities, conduction blocks, and arrhythmias ( 4 ), underscoring ECG’s role as a pragmatic “sentinel” sign.

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