showed a trendp=0.07
conducted a multicenter retrospective study of 130 newly diagnosed older AML patients receiving HMA/venetoclax and found that while pre-existing CKD showed a trend toward lower overall response rates (OR: 0.5; p=0.07), it did not significantly affect overall survival; however, acute kidney injury during treatment was an independent prognostic factor for inferior overall survival (HR: 1.86; p=0.01) [ 15 ].