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Pharmacological restoration of mitochondrial permeability transition pore flickering by high-content drug repurposing.

Pharmacol Res · 2026 · PMC13264520 · PMID 42105820

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Additionally, two compounds, CP-945598 and ezetimibe, showed trends toward increased flickering activity but did not reach statistical significance under the tested conditions, suggesting weak or condition-dependent agonistic effects ( Fig. 5 A).

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