Skeletal muscle knockout of NAD(P)H oxidase 2 delays the development of isotonic diaphragm fatigue in mice.

Free Radic Biol Med · 2025 · PMC13264669 · PMID 40849002

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0.0790

closest p · 1.6× alpha

0.0790

boldest claim

The sentences

approached significancep = 0.079so close (0.05 < p ≤ 0.1)

As such, control animals exhibited a larger F max that approached significance (skmNox2 vs. skmNox2 KO : 20.66 ± 2.66 vs. 16.98 ± 4.56 % Baseline, p = 0.079; comparisons by unpaired student’s t -test) but no difference in T 50 (1.85 ± 2.56 vs. 1.09 ± 1.51 s, p = 0.468; comparisons by unpaired student’s t -test) ( Fig. 7E and F ).

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