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Structural determinants of ligand response specificity in the mast cell activating GPCR, MRGPRX2.

J Biol Chem · 2026 · PMC13266011 · PMID 42107641

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The mean TAN-67 potency at S96F was also an order of magnitude higher than for WT, but the difference did not reach statistical significance in the ANOVA ( Fig. 5 ) (ΔpEC50 1.0).

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