did not reach statistical significanceP = 0.0757
Before the breakpoint, the detection rate showed a gradual upward trend, with an APC of 3.22% per quarter (95% CI: 1.26% to 5.22%, P = 0.0012); after the breakpoint, a downward tendency was observed, although this did not reach statistical significance, with an APC of − 6.28% per quarter (95% CI: −12.76% to 0.67%, P = 0.0757).