<i>De novo</i> design of dual-target mini-binders simultaneously neutralizing <i>Streptococcus equi subspecies zooepidemicus</i> M-like protein and host TNFR1 confers complete protection against lethal infection.

Mater Today Bio · 2026 · PMC13267575 · PMID 42305354

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did not reach statistical significanceno p-value reported

64%) did not reach statistical significance, the survival improvement is meaningful ( Fig. 1 d).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

&lt;i&gt;De novo&lt;/i&gt; design of dual-target mini-binders simultaneously neutralizing &lt;i&gt;Streptococcus equi subspecies zooepidemicus&lt;/i&gt; M-like protein and host TNFR1 confers complete protection against lethal infection.

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<i>De novo</i> design of dual-target mini-binders simultaneously neutralizing <i>Streptococcus equi subspecies zooepidemicus</i> M-like protein and host TNFR1 confers complete protection against lethal infection.