Association of lactate dehydrogenase to albumin ratio with new-onset acute respiratory distress syndrome and all-cause mortality in patients with sepsis: a retrospective cohort study based on the MIMIC-IV database.

BMC Infect Dis · 2026 · PMC13267592 · PMID 42046077

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borderline significanceno p-value reported

After excluding pulmonary infections, the association between LDAR and ARDS was attenuated and reached only borderline significance, indicating the presence of partial confounding.

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a significant trendno p-value reported

The results demonstrated that, compared with Q1, Q4 remained significantly associated with an increased risk of ARDS (OR = 1.435, 95% CI: 1.013–2.036, P = 0.042), with a significant trend across quartiles (P for trend < 0.001) (Supplementary Table S6 ).

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