Analysis and comparison of the trends in burden of congenital musculoskeletal and limb anomalies in China and worldwide from 1990 to 2021.

Medicine (Baltimore) · 2026 · PMC13268457 · PMID 42299591

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an increasing trendno p-value reported

At the global level, compared with 1990, the number of cases in all age groups and DALYs over 10 years old showed an increasing trend in 2021, and the increase in the number of cases was more significant with the increase of age (Fig. 3 E, 3 H).

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did not reach statistical significanceno p-value reported

Monte Carlo simulations showed that the change did not reach statistical significance (95% UI included zero; Table 2 ). 3.5.

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