Diastolic Morning Surge Improves Risk Stratification for Subclinical Left Ventricular Diastolic Dysfunction in Ambulatory-Defined Isolated Diastolic Hypertension.

The incremental improvement compared with Model A did not reach statistical significance (ΔAUC 0.03; p = 0.07), and discrimination did not differ significantly between Model B and Model C (ΔAUC −0.02; p = 0.14), indicating that the primary incremental gain derived specifically from integration of DMS into the fully adjusted framework rather than simple predictor reduction (Table 5 ). 4.6 Calibration and Global Predictive Accuracy Calibration analysis demonstrated meaningful separation between models.

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