An examination into the safety and efficacy of Khapregesic®, a Khaya senegalensis preparation, on physical and psychological wellbeing in women experiencing menopausal symptoms: a randomised, double-blind, placebo-controlled trial.

An analysis of the change in the GCS scores by menopausal status revealed a near-significant group difference in post-menopausal women on the total score ( β : 2.88; 95% CI: −0.07, 5.83; d = 0.48, p = 0.056), a statistically significant group difference on the psychological score ( β : 2.18; 95% CI: 0.47, 3.90; d = 0.63, p = 0.014), but no statistically significant group difference on physical ( p = 1.000) or vasomotor ( p = 0.263) scores ( Figure 2 and Supplementary Table S1 ).

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