Gut Microbiota and Bipolar Disorder: Advances in Translational Applications.

In a randomized double-blind, placebo-controlled trial involving 38 inpatients with bipolar disorder type I, conducted over an 8-week period, although there were decreases in Young Mania Rating Scale and Hamilton Depression Rating Scale scores, they did not reach statistical significance, possibly due to the small sample size [ 54 ].

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