Colonic nutritional and physicochemical parameters drive gut microbiota dysbiosis in obesity: what we learned from the Ob-M-ARCOL model development.

Changes induced by obese conditions were associated with a trend toward reduced α -diversity in the luminal compartment (Shannon: 3.14 in HS‐HP vs 2.95 in HS‐OP; observed: 71.5 vs 64.0, respectively), although this effect did not reach statistical significance ( Figure 3a ).

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