Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time-Restricted Feeding Protection in Crohn's Disease.

Adv Sci (Weinh) · 2026 · PMC13271634 · PMID 41945859

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did not reach statistical significanceno p-value reported

Consistently, metabolomic analysis revealed increased fecal lactate levels in TRF_20h‐fed mice (4‐h refeeding period), although this increase did not reach statistical significance.

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