Risk Factors for Early Chronic Kidney Disease IV-V in Children with Posterior Urethral Valves: A Retrospective Cohort Study.

An important factor which has been reported in literature previously also which may impact progression to early CKD IV–V in children with PUV, is nadir serum creatinine values (>1 mg/dl) have also been associated with poor outcomes in multiple cohorts.[ 2 , 3 , 4 , 5 , 22 , 23 ] In our study, the postoperative creatinine in the absence of UTI was found significantly associated with early progression to CKD IV–V in these children, only in univariate analysis, not on multivariate analysis, although it was approaching significance and may have become statistically significant in a larger sample size.

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