Unraveling the role of HIF-1 in peripheral blood mononuclear cells from older patients with Alzheimer's disease.

Front Aging Neurosci · 2026 · PMC13272122 · PMID 42318557

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a decreasing trendno p-value reported

Analysis of HRE-containing inflammatory markers revealed significantly reduced TNF-α gene expression and a decreasing trend in TREM-1 gene expression in AD patients compared with controls.

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showed a trendno p-value reported

Regarding inflammatory biomarkers, TNF-α gene expression was significantly reduced in PBMCs from AD patients, while TREM-1 gene expression showed a trend toward reduction compared with controls ( Table 3 ).

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