Barely Significant
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Neuropathological study of the effects of aducanumab anti-Aβ immunotherapy on patients with Alzheimer's disease.

Acta Neuropathol · 2026 · PMC13272220 · PMID 42301522

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A modest trend towards expanded GFAP expression was similarly observed, but did not reach statistical significance (Fig. 4 d, e).

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a nonsignificant trendno p-value reported
Despite reduced Aβ burden in aducanumab-treated cases, there was only a nonsignificant trend towards increased IBA1 coverage (Fig. 4 a, b).

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