In contrast, homozygous MYZAP -mutant hiPSC-CMs demonstrated a pronounced increase in Vmax (dV/dt; homozygous: 43.1 ± 9.4 V/s; control: 24.3 ± 5.9 V/s) but did not reach statistical significance.
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Unveiling cellular mechanisms underlying MYZAP related dilated cardiomyopathy using patient specific hiPSC cardiomyocytes.
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