Supportive care interventions in hematopoietic stem cell transplantation: a systematic review and meta-analysis.

Our exploratory meta-analyses generally mirrored the qualitative synthesis: exercise interventions showed a trend toward improvements in QOL but no impact on psychological distress, consistent with previous reviews, which found benefits for QOL but no effects on distress. 197 , 198 The broader literature suggests that exercise may confer benefits through reductions in fatigue and sleep disturbance as well as i

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With ρ = 0.5, the pooled common-effect model suggested a small improvement in overall QOL with exercise (MD, 3.64; 95% CI, 0.04-7.23), whereas the random-effects model showed a nonsignificant trend (MD, 3.64; 95% CI, −0.13 to 7.40; I 2 = 0%).

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