Although the time spent in the center did not differ significantly between the CV@MT-NPs (7.55 ± 3.64 s) and LPS (0.25 ± 0.61 s) groups, a clear trend toward improvement was observed ( Fig. 3 H), implying partial mitigation of anxiety-like behavior.
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A multistage micro-nano biosystem prevents sepsis-associated encephalopathy through coordinated neuroinflammation suppression and gut-brain axis modulation.
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