Machine learning-guided multimodal profiling defines perturbed immune states at the time of cancer diagnosis.

CD177 + neutrophils), was evident, but this did not reach statistical significance, primarily due to high inter-patient variability ( Supplemental Fig. 1 ).

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Highly significant genes are shown as volcano plots, heatmaps [ 30 ], bubble plots [ 31 ], and upset plots [ 32 ].

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