Dapagliflozin ameliorates motor deficits in a Parkinson's disease model induced by 6-OHDA: An integrative in vivo and in silico approach from α-synuclein/A2AAR/TH/TNF-α to APAF-1/caspase-3 modulation.

Inflammopharmacology · 2026 · PMC13275567 · PMID 41998450

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a decreasing trendno p-value reported

Compared with the PC group, a decreasing trend in terms of ipsilateral paw use was observed across all the treatment groups.

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did not reach statistical significanceno p-value reported

Vertical activity also tended to increase post-treatment in the treatment groups compared with the PC group, although this trend did not reach statistical significance (Fig. 3 a).

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