Predictors of Pathological Complete Response and Patient-Reported Outcomes During Neoadjuvant Chemotherapy in Early Breast Cancer: A Single-Center Retrospective Cohort Study.

Cureus · 2026 · PMC13276464 · PMID 42326181

Europe PMC DOI

hedged sentence

0.0990

closest p · 2.0× alpha

0.0990

boldest claim

The sentences

did not reach statistical significancep=0.099so close (0.05 < p ≤ 0.1)

EORTC global health scores declined by a clinically meaningful ≥10 points in 51/149 patients (34.2%), with a numerically larger burden in luminal B and TNBC than in HER2-positive disease - a difference that did not reach statistical significance (χ2=4.63, df=2, p=0.099) but is consistent with the more intensive cytotoxic profile of regimens used in those subtypes.

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