Addition of CAD polygenic risk score to coronary artery calcium score enhances prediction of MACE.

Front Cardiovasc Med · 2026 · PMC13276707 · PMID 42325687

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

did not reach statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

The RS-II estimate, while directionally consistent, did not reach statistical significance ( p = 0.052), likely reflecting reduced statistical power in that subcohort ( n = 2,151).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.